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Alternative name
CSDD2, FLJ16517, lin 28 homolog B (C. elegans), Lin 28B, Lin28, LIN28B, Protein lin 28 homolog B antibody
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Catalog
A004786
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,IHC,IF,WB
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PurificationImmunogen affinity purified
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Immunogenlin-28 homolog B (C. elegans)
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IHCImmunohistochemistry of paraffin-embedded human spleen using A004786(Lin28B-specific antibody) at dilution of 1:50
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Western BlotTransfected HEK-293 cells were subjected to SDS PAGE followed by western blot with A004786( Lin28B-specific Antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200;IF:1:10-1:100
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Product Description specificalLIN28B, also named as CSDD2, belongs to the lin-28 family. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Lin2B is stage-specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells; however, it is suppressed in most adult tissues except for skeletal and cardiac muscle. Lin28B shares 78% sequence identity with LIN28A, with some unknown functions. This antibody is specific to LIN28B.
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Gene nameLIN28B
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locationCytoplasm,Nucleus
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Uniprot IDQ6ZN17
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Calculated M.W.28kDa
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