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Alternative name
FH, FHC, LDL receptor, LDLR antibody
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Catalog
A004742
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenlow density lipoprotein receptor
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IHCImmunohistochemistry of paraffin-embedded human brain tissue slide using A004742( LDLR Antibody) at dilution of 1:200 heat mediated antigen retrieved with Sodium Citrate buffer (pH6).
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A004742(LDLR antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalBinds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits._x000D_(Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes, but not through a direct interaction with viral proteins (PubMed:10535997, PubMed:12615904). Acts as a receptor for vesicular stomatitis virus (PubMed:23589850). In case of HIV-1 infection, may function as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells (PubMed:11100124).
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Gene nameLDLR
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Uniprot IDP01130
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Observed M.W.150-160 kDa
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