anti-KCNAB2 antibody

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  • Alternative name

    KCNA2B, KCNK2 antibody

  • Catalog
    A004479
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB
  • PurificationImmunogen affinity purified
  • Immunogenpotassium voltage-gated channel, shaker-related subfamily, beta member 2
  • Recommended dilutionWB : 1:500-1:5000
  • Product Description specificalCytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (PubMed:7649300, PubMed:11825900). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore (PubMed:7649300, PubMed:11825900). Promotes KCNA4 channel closure (PubMed:7649300, PubMed:11825900). Modulates the functional properties of KCNA5 (By similarity). Enhances KCNB2 channel activity (By similarity). Binds NADPH and has NADPH- dependent aldoketoreductase activity (By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4- nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) (By similarity).
  • Gene nameKCNAB2
  • Uniprot IDQ13303
  • Observed M.W.38kd




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