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Alternative name
HIRS 1, insulin receptor substrate 1, IRS 1, IRS1 antibody
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Catalog
A004400
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,IP,IF
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PurificationImmunogen affinity purified
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Immunogeninsulin receptor substrate 1
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A004400(IRS1 antibody) at dilution of 1:100
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Western BlotA549 cells were subjected to SDS PAGE followed by western blot with A004400(IRS1 antibody) at dilution of 1:400
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalMay mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
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Gene nameIRS1
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Uniprot IDP35568
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Observed M.W.160-185 kDa
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