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Alternative name
ACO3, FLJ23381, IRE BP 2, IREB2, Iron regulatory protein 2, IRP2, IRP2AD antibody
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Catalog
A004384
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IF
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PurificationImmunogen affinity purified
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Immunogeniron-responsive element binding protein 2
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalRNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'- UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
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Gene nameIREB2
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Uniprot IDP48200
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Observed M.W.90-105 kDa
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