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Alternative name
CD49D, IA4, Integrin alpha 4, Integrin alpha IV, ITGA4, VLA 4 subunit alpha antibody
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Catalog
A004346
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenintegrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
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IHCImmunohistochemistry of paraffin-embedded human tonsillitis tissue slide using A004346( Integrin alpha-4 Antibody) at dilution of 1:50
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A004346(ITGA4 antibody) at dilution of 1:3000
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Recommended dilutionWB:1:1000-1:10000;IHC:1:20-1:200
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Product Description specificalITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. I It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
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Gene nameITGA4
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Uniprot IDP13612
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Calculated M.W.115kDa
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Observed M.W.115 kDa
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