anti-ING3 antibody

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  • Alternative name

    Eaf4, FLJ20089, ING2, ING3, Inhibitor of growth protein 3, p47ING3 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman, Mouse
  • Applications Tested/SuitableELISA,IHC,WB
  • PurificationImmunogen affinity purified
  • Immunogeninhibitor of growth family, member 3
  • IHCImmunohistochemistry of paraffin-embedded human breast cancer using A004311(ING3 antibody) at dilution of 1:100
  • Western Blotmouse uterus tissue were subjected to SDS PAGE followed by western blot with A004311(ING3 antibody) at dilution of 1:800
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalComponent of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
  • Gene nameING3
  • Uniprot IDQ9NXR8
  • Observed M.W.47 kDa

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