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Alternative name
CRFB4, D21S58, D21S66 antibody
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Catalog
A004214
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogeninterleukin 10 receptor, beta
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalShared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
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Gene nameIL10RB
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Uniprot IDQ08334
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Observed M.W.42-45 kDa
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