anti-IKBKG antibody

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  • Alternative name

    FIP3, NEMO antibody

  • Catalog
    A004202
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,IF
  • PurificationImmunogen affinity purified
  • Immunogeninhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • IHCImmunohistochemistry of paraffin-embedded human kidney using A004202(IKBKG antibody) at dilution of 1:50
  • Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A004202(IKBKG antibody) at dilution of 1:800
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalRegulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B- mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
  • Gene nameIKBKG
  • Uniprot IDQ9Y6K9
  • Observed M.W.48 kDa




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