anti-IGHD antibody

Contact Us
  • Alternative name

    FLJ00382, FLJ46727, IGHD antibody

  • Catalog
    A004183
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman
  • Applications Tested/SuitableELISA,WB,IHC
  • PurificationImmunogen affinity purified
  • Immunogenimmunoglobulin heavy constant delta
  • IHCImmunohistochemistry of paraffin-embedded human tonsillitis tissue slide using A004183( IGHD Antibody) at dilution of 1:50
  • Western BlotRaji cells were subjected to SDS PAGE followed by western blot with A004183(IGHD antibody) at dilution of 1:600
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalIgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.
  • Gene nameIGHD
  • Uniprot IDP01880
  • Observed M.W.55-70 kDa


Related products with anti-IGHD antibody

Inquiry About anti-IGHD antibody If you hope to order it or contact us directly, please contact us via sales@biobool.com. We will get back to you in 12hrs,Thanks!