anti-IFT57 antibody

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  • Alternative name

    DERP8, ESRRBL1, HIPPI antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,IP
  • PurificationImmunogen affinity purified
  • Immunogenintraflagellar transport 57 homolog (Chlamydomonas)
  • IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A004160(IFT57 antibody) at dilution of 1:50
  • Western Blotmouse retina tissue were subjected to SDS PAGE followed by western blot with A004160(IFT57 antibody) at dilution of 1:1000
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalRequired for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
  • Gene nameIFT57
  • Uniprot IDQ9NWB7
  • Observed M.W.49kd

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