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Alternative name
DERP8, ESRRBL1, HIPPI antibody
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Catalog
A004160
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenintraflagellar transport 57 homolog (Chlamydomonas)
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A004160(IFT57 antibody) at dilution of 1:50
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Western Blotmouse retina tissue were subjected to SDS PAGE followed by western blot with A004160(IFT57 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalRequired for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
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Gene nameIFT57
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Uniprot IDQ9NWB7
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Observed M.W.49kd
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