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Alternative name
1 8D, IFITM2 antibody
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Catalog
A004142
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,IP,IHC,IF,WB
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PurificationImmunogen affinity purified
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Immunogeninterferon induced transmembrane protein 2 (1-8D)
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IHCImmunohistochemistry of paraffin-embedded human breast cancer slide using A004142( IFITM2 Antibody) at dilution of 1:50
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Western BlotMCF-7 cells were subjected to SDS PAGE followed by western blot with A004142( IFITM2 Antibody) at dilution of 1:2000
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Recommended dilutionWB : 1:1000-1:10000
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Product Description specificalIFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
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Gene nameIFITM2
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Uniprot IDQ01629
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Observed M.W.15kd
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