-
Alternative name
ISG58, RI58 antibody
-
Catalog
A004139
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
Immunogeninterferon-induced protein with tetratricopeptide repeats 5
-
IHCImmunohistochemistry of paraffin-embedded human skin cancer tissue slide using A004139( IFIT5 Antibody) at dilution of 1:50
-
Western BlotA375 cells were subjected to SDS PAGE followed by western blot with A004139(IFIT5 antibody) at dilution of 1:200
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalInterferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP- RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.
-
Gene nameIFIT5
-
Uniprot IDQ13325
-
Observed M.W.56-58 kDa,48 kDa
-