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Alternative name
Abeta degrading protease, FLJ35968, IDE, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN antibody
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Catalog
A004116
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogeninsulin-degrading enzyme
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IHCImmunohistochemistry of paraffin-embedded human kidney using A004116(IDE antibody) at dilution of 1:50
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Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A004116(IDE antibody) at dilution of 1:300
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalPlays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. _x000D_(Microbial infection) The membrane-associated isoform acts as an entry receptor for varicella-zoster virus (VZV).
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Gene nameIDE
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Uniprot IDP14735
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Observed M.W.100-120 kDa
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