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Alternative name
ANAPC5, APC5, Cyclosome subunit 5 antibody
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Catalog
A000387
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenanaphase promoting complex subunit 5
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A000387(ANAPC5 antibody) at dilution of 1:50
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Western BlotBxPC-3 cells were subjected to SDS PAGE followed by western blot with A000387(ANAPC5 antibody) at dilution of 1:500
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Recommended dilutionWB :1:200-1:2000;IHC:1:20-1:200
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Product Description specificalComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
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Gene nameANAPC5
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locationcytosol,ucleoplasm
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Uniprot IDQ9UJX4
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Calculated M.W.85kDa
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Observed M.W.85 kDa
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