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Alternative name
ERF3B antibody
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Catalog
A003681
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenG1 to S phase transition 2
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A003681(GSPT2 antibody) at dilution of 1:100
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Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A003681(GSPT2 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:1000-1:10000
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Product Description specificalInvolved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
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Gene nameGSPT2
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Uniprot IDQ8IYD1
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Observed M.W.69 kDa
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