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Alternative name
GBP 5, GBP TA antigen, GBP5, GTP binding protein 5, guanylate binding protein 5 antibody
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Catalog
A003376
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,IHC,IF,WB,FC
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PurificationImmunogen affinity purified
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Immunogenguanylate binding protein 5
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A003376(GBP5 antibody) at dilution of 1:100
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Western BlotU-937 cells were subjected to SDS PAGE followed by western blot with A003376( GBP5 Antibody) at dilution of 1:1500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalAs an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847).
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Gene nameGBP5
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Uniprot IDQ96PP8
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Observed M.W.65 kDa, 55 kDa
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