anti-Alpha E catenin antibody

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  • Alternative name

    Alpha catenin, Alpha E catenin, Cadherin associated protein, CAP102, Catenin alpha 1, CTNNA1, α-catenin, α-E-catenin, αE-catenin antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,IF,FC,IP
  • PurificationImmunogen affinity purified
  • Immunogencatenin (cadherin-associated protein), alpha 1, 102kDa
  • IHCImmunohistochemistry of paraffin-embedded human stomach tissue slide using A000327( CTNNA1 Antibody) at dilution of 1:50
  • Western Blotmouse uterus tissue were subjected to SDS PAGE followed by western blot with A000327(CTNNA1 Antibody) at dilution of 1:2000
  • Recommended dilutionWB :1:1000-1:10000;IHC:1:20-1:200;IP:1:200-1:2000;IF:1:10-1:100
  • Product Description specificalAlpha catenin is an essential component of adherens junctions that connects E-cadherin-β-catenin complexes with the actin cytoskeleton. It also recruits a range of other important proteins to developing intercellular junctions. Three alpha catenins exist in human: alpha-E-catenin, alpha-N-catenin, and alpha-T-catenin, which share substantial amino-acid sequence similarity but have distinct tissue distribution. alpha-E-catenin is ubiquitously expressed, alpha-N-catenin is restricted to neuronal tissue, and alpha-T-catenin is primarily expressed in heart tissue. Reduced levels of alpha-E-catenin protein seem to be characteristic of many different human cancers, including malignant tumours of the breast, colon, stomach, oesophagus, bladder and liver. In addition, the loss of alpha-E-catenin often correlates with the degree of tumour differentiation and metastasis.
  • Gene nameCTNNA1
  • locationCytoplasm,Cytoskeleton,ell membrane
  • Uniprot IDP35221
  • Calculated M.W.100kDa
  • Observed M.W.100 kDa

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