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Alternative name
FGFR signaling adaptor SNT, FGFR substrate 2, FRS2, FRS2A, FRS2alpha, SNT, SNT 1, SNT1 antibody
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Catalog
A003225
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,WB,IF
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PurificationImmunogen affinity purified
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Immunogenfibroblast growth factor receptor substrate 2
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A003225(FRS2 antibody) at dilution of 1:50
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Western BlotMCF-7 cells were subjected to SDS PAGE followed by western blot with A003225( FRS2 Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalAdapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
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Gene nameFRS2
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Uniprot IDQ8WU20
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Observed M.W.68 kDa
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