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Alternative name
PTK5, RAK antibody
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Catalog
A003224
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogenfyn-related kinase
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A003224(FRK antibody) at dilution of 1:50
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A003224(FRK antibody) at dilution of 1:800
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalNon-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
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Gene nameFRK
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Uniprot IDP42685
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Observed M.W.54-57 kDa
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