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Alternative name
TTC11 antibody
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Catalog
A003132
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,IF,IP,WB
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PurificationImmunogen affinity purified
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Immunogenfission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
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IHCImmunohistochemistry of paraffin-embedded human brain using A003132(FIS1 antibody) at dilution of 1:25
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Recommended dilutionWB : N/A
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Product Description specificalInvolved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
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Gene nameFIS1
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Uniprot IDQ9Y3D6
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Observed M.W.17 kDa
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