StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Mouse ,Rat
PurificationImmunogen affinity purified
ImmunogenFYVE, RhoGEF and PH domain containing 5
IHCImmunohistochemistry of paraffin-embedded human lung using A003086(FGD5 antibody) at dilution of 1:100
Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A003086(FGD5 antibody) at dilution of 1:500
Recommended dilutionWB : 1:200-1:2000
Product Description specificalActivates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.