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Alternative name
KIND3, MIG2B, URP2 antibody
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Catalog
A003078
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogenfermitin family homolog 3 (Drosophila)
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IHCImmunohistochemistry of paraffin-embedded human lymphoma using A003078(FERMT3 antibody) at dilution of 1:50
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A003078(FERMT3 antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalPlays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity). _x000D_Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.
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Gene nameFERMT3
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Uniprot IDQ86UX7
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Observed M.W.72-76kd
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