-
Alternative name
FBX7 antibody
-
Catalog
A003049
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse
-
Applications Tested/SuitableELISA,WB,IHC,IP
-
PurificationImmunogen affinity purified
-
ImmunogenF-box protein 7
-
IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A003049(FBXO7 antibody) at dilution of 1:100
-
Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A003049(FBXO7 antibody) at dilution of 1:1000
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalSubstrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
-
Gene nameFBXO7
-
Uniprot IDQ9Y3I1
-
Observed M.W.58.5 kDa
-