StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Mouse ,Rat
PurificationImmunogen affinity purified
ImmunogenFas associated factor family member 2
IHCImmunohistochemistry of paraffin-embedded human testis using A002947(FAF2 antibody) at dilution of 1:50
Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A002947(FAF2 antibody) at dilution of 1:1000
Recommended dilutionWB : 1:500-1:5000
Product Description specificalPlays an important role in endoplasmic reticulum- associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223).