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Alternative name
C10orf69, KE04, KEO4, SPFH1 antibody
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Catalog
A002848
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP,IF
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PurificationImmunogen affinity purified
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ImmunogenER lipid raft associated 1
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IHCImmunohistochemistry of paraffin-embedded human testis using A002848(ERLIN1 antibody) at dilution of 1:100
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Western Blotrat pancreas tissue were subjected to SDS PAGE followed by western blot with A002848(ERLIN1 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalComponent of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
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Gene nameERLIN1
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Uniprot IDO75477
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Observed M.W.39 kDa
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