IHCImmunohistochemistry of paraffin-embedded human testis using A002832(ERCC1 antibody) at dilution of 1:50
Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A002832(ERCC1 antibody) at dilution of 1:300
Recommended dilutionWB : 1:500-1:5000
Product Description specificalIsoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.