anti-AlaRS antibody

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  • Alternative name

    AARS, Alanine tRNA ligase, alanyl tRNA synthetase, AlaRS antibody

  • Catalog
    A000276
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC
  • PurificationImmunogen affinity purified
  • Immunogenalanyl-tRNA synthetase
  • IHCImmunohistochemistry of paraffin-embedded human liver using A000276(AARS antibody) at dilution of 1:100
  • Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A000276(AARS antibody) at dilution of 1:400
  • Recommended dilutionWB :1:200-1:1000;IHC:1:20-1:200;IF:1:20-1:200;IP:1:200-1:2000
  • Product Description specificalAARS(alanyl-tRNA synthetase) is also named as AlaRS(alanine tRNA ligase 1, cytoplasmic), renal carcinoma antigen NY-REN-42 and belongs to the class-II aminoacyl-tRNA synthetase family. It can interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. AARS consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs(PMID:19661429).
  • Gene nameAARS
  • locationCytoplasm
  • Uniprot IDP49588?
  • Calculated M.W.107kDa
  • Observed M.W.107 kDa


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