anti-EIF3J antibody

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  • Alternative name

    EIF3S1 antibody

  • Catalog
    A002711
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,IF,IP
  • PurificationImmunogen affinity purified
  • Immunogeneukaryotic translation initiation factor 3, subunit J
  • IHCImmunohistochemistry of paraffin-embedded human breast cancer using A002711(EIF3J antibody) at dilution of 1:100
  • Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A002711(EIF3J antibody) at dilution of 1:500
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
  • Gene nameEIF3J
  • Uniprot IDO75822
  • Observed M.W.35 kDa




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