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Alternative name
17 beta HSD 5, 3 alpha HSD type 2, 3 alpha HSD type II, brain, AKR1C3, DD 3, DD3, DDX, Dihydrodiol dehydrogenase 3, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, Indanol dehydrogenase, KIAA0119, PGFS, Prostaglandin F synthase antibody
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Catalog
A000262
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenaldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A000262(AKR1C3 antibody) at dilution of 1:100
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Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A000262(AKR1C3 antibody) at dilution of 1:1000
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Recommended dilutionWB :1:500-1:5000;IP:1:500-1:5000;IHC:1:20-1:200
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Product Description specificalCatalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.
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Gene nameAKR1C3
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locationCytoplasm
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Uniprot IDP42330
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Calculated M.W.37kDa,observed 34kDa
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Observed M.W.34 kDa
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