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Alternative name
AKR1A1, Alcohol dehydrogenase [NADP+], Aldehyde reductase, ALDR1, ALR, ARM, DD3 antibody
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Catalog
A000260
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenaldo-keto reductase family 1, member A1 (aldehyde reductase)
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A000260(AKR1A1 antibody) at dilution of 1:500
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Recommended dilutionWB :1:200-1:2000;IP:1:200-2000;IF:1:50-500
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Product Description specificalCatalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4- nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D- glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
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Gene nameAKR1A1
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Uniprot IDP14550
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Calculated M.W.37kDa
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Observed M.W.36 kDa
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