anti-DKK1 antibody

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  • Alternative name

    Dickkopf 1, Dickkopf related protein 1, DKK 1, DKK1, hDkk 1, SK antibody

  • Catalog
    A002401
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IF,IHC
  • PurificationImmunogen affinity purified
  • Immunogendickkopf homolog 1 (Xenopus laevis)
  • IHCImmunohistochemistry of paraffin-embedded human gliomas tissue slide using A002401( DKK1 Antibody) at dilution of 1:200
  • Western Blothuman placenta tissue were subjected to SDS PAGE followed by western blot with A002401(DKK1 antibody) at dilution of 1:500
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalAntagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
  • Gene nameDKK1
  • Uniprot IDO94907
  • Observed M.W.30-35 kDa




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