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Alternative name
Ah receptor, AHR, aryl hydrocarbon receptor, bHLHe76 antibody
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Catalog
A000231
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenaryl hydrocarbon receptor
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IHCImmunohistochemistry of paraffin-embedded human brain using A000231(AHR antibody) at dilution of 1:100
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Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A000231(AHR antibody) at dilution of 1:1000
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Recommended dilutionWB :1:200-1:2000;IP:1:200-1:2000;IHC:1:20-1:200
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Product Description specificalLigand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
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Gene nameAHR
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locationCytoplasm,Nucleus
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Uniprot IDP35869
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Calculated M.W.96kDa,observed 105kDa
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Observed M.W.105kd
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