anti-Cysteine dioxygenase type 1 antibody
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Alternative name
CDO, CDO I, CDO1, Cysteine dioxygenase type 1, cysteine dioxygenase, type I antibody
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Catalog
A002183
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse , Rat
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogencysteine dioxygenase, type I
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A002183(CDO1 antibody) at dilution of 1:100
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Western Blotmouse liver tissue were subjected to SDS PAGE followed by western blot with A002183(CDO1 antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
IP : 1:200-1:2000
IHC : 1:20-1:200
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Product Description specificalCDO1(cysteine dioxygenase type 1) is also named as CDO and belongs to the cysteine dioxygenase family. It is an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid (3-sulfinoalanine) and CDO1 is one of the most highly regulated metabolic enzymes responding to diet(PMID:19011731). The expression of CDO can significantly decrease the level of intracellular cysteine and this reduction is also associated with a decrease in total glutathione levels(PMID:17327371). Cysteine dioxygenase (CDO) plays a critical role in the regulation of cellular cysteine concentration andmultiple forms of CDO (23 kDa, 25 kDa, and 68 kDa) have been claimed based upon separation and detection using S
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Uniprot IDQ16878
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Calculated M.W.23 kDa
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