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Alternative name
CBAS3, CP7B, CYP7B1, Cytochrome P450 7B1, Oxysterol 7 alpha hydroxylase, SPG5A antibody
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Catalog
A002177
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogencytochrome P450, family 7, subfamily B, polypeptide 1
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IHCImmunohistochemistry of paraffin-embedded human brain tissue slide using A002177( CYP7B1 Antibody) at dilution of 1:50
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Western BlotA431 cells were subjected to SDS PAGE followed by western blot with A002177( CYP7B1 Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalOxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) from 25- hydroxycholesterol (PubMed:10588945). Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25- dihydroxycholesterol (7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (By similarity).
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Gene nameCYP7B1
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Uniprot IDO75881
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Observed M.W.50-55 kDa
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