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Alternative name
CREM, hCREM 2, ICER, Inducible cAMP early repressor antibody
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Catalog
A001970
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,WB,IP
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PurificationImmunogen affinity purified
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ImmunogencAMP responsive element modulator
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A001970(CREM antibody) at dilution of 1:50
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Western Blotrat testis tissue were subjected to SDS PAGE followed by western blot with A001970( CREM Antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalTranscriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550). _x000D_Isoform 6: May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter.
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Gene nameCREM
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Uniprot IDQ03060
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Observed M.W.38 kDa
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