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Alternative name
Coatomer subunit epsilon, COPE, Epsilon coat protein, epsilon COP, FLJ13241 antibody
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Catalog
A001865
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IF,IHC
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PurificationImmunogen affinity purified
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Immunogencoatomer protein complex, subunit epsilon
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer tissue slide using A001865( COPE Antibody) at dilution of 1:50
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Western BlotPC-3 cells were subjected to SDS PAGE followed by western blot with A001865(COPE antibody) at dilution of 1:500
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalThe coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP- ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
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Gene nameCOPE
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Uniprot IDO14579
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Observed M.W.36 kDa
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