anti-CLSTN1 antibody

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  • Alternative name

    CS1, KIAA0911 antibody

  • Catalog
    A001776
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman, Mouse ,Rat
  • Applications Tested/SuitableELISA,WB
  • PurificationImmunogen affinity purified
  • Immunogencalsyntenin 1
  • Recommended dilutionWB : 1:500-1:5000
  • Product Description specificalInduces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2- mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1- binding. May modulate calcium-mediated postsynaptic signals (By similarity).
  • Gene nameCLSTN1
  • Uniprot IDO94985
  • Observed M.W.109kd


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