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Alternative name
CDGSH2, ERIS, ZCD2 antibody
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Catalog
A001718
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenCDGSH iron sulfur domain 2
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IHCImmunohistochemistry of paraffin-embedded human kidney using A001718(CISD2 antibody) at dilution of 1:100
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Western Blotmouse kidney tissue were subjected to SDS PAGE followed by western blot with A001718(CISD2 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalRegulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
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Gene nameCISD2
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Uniprot IDQ8N5K1
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Observed M.W.13-15 kDa
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