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Alternative name
A18HNRNP, CIRP antibody
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Catalog
A001715
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,IP,IF,WB
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PurificationImmunogen affinity purified
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Immunogencold inducible RNA binding protein
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A001715(CIRBP antibody) at dilution of 1:100
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Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A001715( CIRBP Antibody) at dilution of 1:600
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalCold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold- induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
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Gene nameCIRBP
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Uniprot IDQ14011
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Observed M.W.19 kDa
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