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Alternative name
2200003E03Rik, Acidic mammalian chitinase, AMCase, CHIA, CHIT2, chitinase, acidic, DKFZp313J1722, Lung specific protein TSA1902, RP5 1125M8.1, TSA1902 antibody
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Catalog
A001650
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogenchitinase, acidic
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IHCImmunohistochemistry of paraffin-embedded human stomach using A001650(CHIA antibody) at dilution of 1:50
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Western Blotmouse lung tissue were subjected to SDS PAGE followed by western blot with A001650(CHIA antibody) at dilution of 1:500
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalDegrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.
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Gene nameCHIA
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Uniprot IDQ9BZP6
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Observed M.W.52 kDa
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