anti-CEP290 antibody

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  • Alternative name

    BBS14, KIAA0373, NPHP6,LCA10, MKS4, Nephrocystin 6, rd16, SLSN6, Tumor antigen se2 2 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IP,IHC,IF
  • PurificationImmunogen affinity purified
  • Immunogencentrosomal protein 290kDa
  • IHCImmunohistochemistry of paraffin-embedded human placenta using A001602(CEP290 antibody) at dilution of 1:50
  • Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A001602( CEP290 Antibody) at dilution of 1:600
  • Recommended dilutionWB : 1:200-1:2000 IP : 1:500-1:5000 IHC : 1:20-1:200 IF : 1:50-1:500
  • Product Description specificalStudies in the Chlamydomonas model system has shown that the ciliary protein CEP290 is a critical component of these Y-link junctions. Additionally, numerous studies have demonstrated that CEP290’s function is critical for IFT—in CEP290 knockdown experiments, many proteins that would normally localize to the cilium fail to do so, and cilium formation is disrupted or absent. Mutations in CEP290 are accountable for cases of nephronophthisis, Leber congenital amaurosis and Joubert syndrome. In IF analtsis of HeLa cells, the white arrows show centrosome and cilium staining.
  • Gene nameCEP290
  • Uniprot IDO15078
  • Calculated M.W.290 kDa, 150-180 kDa, 80 kDa,60 kDa
  • Observed M.W.290 kDa, 150-180 kDa, 80 kDa,60 kDa

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