StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Mouse ,Rat
PurificationImmunogen affinity purified
Immunogencell division cycle 26 homolog (S. cerevisiae)
IHCImmunohistochemistry of paraffin-embedded mouse brain tissue slide using A001524( CDC26 Antibody) at dilution of 1:50
Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A001524( CDC26 Antibody) at dilution of 1:300
Recommended dilutionWB : 1:200-1:1000
Product Description specificalComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.