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Alternative name
MIC11, MIN1, MIN2, MIN3, MSK21 antibody
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Catalog
A001489
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,FC,IF
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PurificationImmunogen affinity purified
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ImmunogenCD59 molecule, complement regulatory protein
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IHCImmunohistochemistry of paraffin-embedded human ovary tumor using A001489(CD59 antibody) at dilution of 1:100
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Western BlotBxPC-3 cells were subjected to SDS PAGE followed by western blot with A001489(CD59 antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalPotent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase._x000D_The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
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Gene nameCD59
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Uniprot IDP13987
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Observed M.W.18-20 kDa
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