-
Alternative name
SIGLEC3 antibody
-
Catalog
A001467
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,WB,IHC,IF
-
PurificationImmunogen affinity purified
-
ImmunogenCD33 molecule
-
IHCImmunohistochemistry of paraffin-embedded human spleen using A001467(CD33 antibody) at dilution of 1:100
-
Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A001467(CD33 antibody) at dilution of 1:600
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalPutative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
-
Gene nameCD33
-
Uniprot IDP20138
-
Observed M.W.67 kDa
-