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Alternative name
AL024079, C78928, CD2 associated protein, Cd2ap, METS 1 antibody
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Catalog
A001455
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenCD2-associated protein
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalSeems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T- cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
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Gene nameCd2ap
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Uniprot IDQ9Y5K6
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Observed M.W.70 kDa
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