anti-ACTN4 antibody

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  • Alternative name

    ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, DKFZp686K23158, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,IF,IP,FC
  • PurificationImmunogen affinity purified
  • Immunogenactinin, alpha 4
  • IHCImmunohistochemistry of paraffin-embedded human breast cancer using A000123(ACTN4 antibody) at dilution of 1:100
  • Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A000123(ACTN4 antibody) at dilution of 1:500
  • Recommended dilutionWB :1:500-1:5000;IHC:1:20-1:200;IP:1:500-1:5000;IF:1:10-1:100
  • Product Description specificalF-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778).
  • Gene nameACTN4
  • locationCytoplasm,Nucleus
  • Uniprot IDO43707
  • Calculated M.W.105kDa
  • Observed M.W.100-105 kDa

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