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Alternative name
CACH5, CACNL1A5 antibody
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Catalog
A001171
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogencalcium channel, voltage-dependent, N type, alpha 1B subunit
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IHCImmunohistochemistry of paraffin-embedded mouse brain tissue slide using A001171( CACNA1B Antibody) at dilution of 1:100 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A001171(CACNA1B antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalVoltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin- IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
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Gene nameCACNA1B
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Uniprot IDQ00975
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Observed M.W.262 kDa
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