Human ADIPOQ ELISA Kit

Alternative name
Human 30 kDa adipocyte complement-related protein ELISA Kit;Human adipocyte complement-related 30 kDa protein ELISA Kit;Human ACRP30 ELISA Kit;Human Adipocyte, C1q and collagen domain-containing protein ELISA Kit;Human adipose most abundant gene transcript 1 protein ELISA Kit;Human APM-1 ELISA Kit;Human Gelatin-binding protein ELISA Kit;Human ACDC ELISA Kit;Human APM1 ELISA Kit;Human GBP28 ELISA Kit;Human ADIPQTL1 ELISA Kit;Human ADPN ELISA Kit;Human adiponectin, C1Q and collagen domain containing ELISA Kit;Human adiponectin ELISA Kit;Human adipose specific collagen-like factor ELISA Kit;Human gelatin-binding protein 28 ELISA Kit;
Catalog
E000915
species
Human
GeneADIPOQ
SpecificitySerum of the cited species was diluted (1:505) and used as sample in this assay system. No cross reactivity was detected: Horse, Cow, Chicken, Rabbit, Dog, Guinea pig, Sheep, Mouse, Goat, Donkey, Rat, Cat
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
SensitivityThe analytical sensitivity of the ELISA E09 yields < 0.6 ng/ml (equal to < 0.06 ng per well; as 2xSD of zero standard in 16fold determination).
Intended UseHuman ADIPOQ ELISA Kit allows for the in vitro quantitative determination of ADIPOQ , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Categories/FamilyCardiovascular; Diabetes & Obesity; Brain Disorders & Neuroscience; Cytokines & Cell Signalling; Endocrinology ; Hormones; Gastroenterology; Research Assays; Assay Categories
Product Description
specificalBackground: Adiponectin is a 30kDa protein which percentage in serum proteins is 0.01%. It is mainly synthesized by Adipocytes, but also muscle cells and hepatocytes have the ability to synthesize Adiponectin. Until now, IGF-I is the only known natural inductor of the synthesis. It consists of a Collagen-like N-terminal and a globular C-terminal domain [1]. In vivo Adiponectin appears with different oligomers. Beside the trimer and ditrimer also high molecular multimers exist [1-3]. Up to now two different receptors are known, both receptors are ubiquitary expressed, though the distribution in the tissues varies. The Adiponectin Receptor 1 (AdipoR1) is especially in muscle- and AdipoR2 in liver tissue synthesized [4]. The significance for the human organism is not clear until now. First studies show, that adiponectin correlates negatively with BMI and thus it could have relevance for the energy metabolism for example through the regulation of fatty acid oxidation. Beside the correlation with BMI, Adiponectin level is associated with the Insulin-Resistance [5-7] and so also linked with Type II Diabetes. Adiponectin is associated also with glucose- und lipometabolism [8, 9]. Furthermore it is involved in inflammatory processes [11-15] and therewith it is of importance for appearance of arteriosclerosis [4, 5, 16] and coronaritis [17, 18], thus the determination of Adiponectin level in plasma could serve to estimate the risk of coronary disease [19, 20]. Beside this Adiponectin influences further physiological processes as for example the angiogenesis [21, 22].
Human Adiponectin Protein information
Uniprot ID ADIPO_HUMAN
Uniprot AC Q15848; Q58EX9;
UniGene Hs.80485;
GeneID 9370
KEGG hsa:9370;
Human Adiponectin Protein SEQUENCE
SEQUENCE 244 AA; 26414 MW; 64D8C6C1204B1018 CRC64;
MLLLGAVLLL LALPGHDQET TTQGPGVLLP LPKGACTGWM AGIPGHPGHN
GAPGRDGRDG TPGEKGEKGD PGLIGPKGDI GETGVPGAEG PRGFPGIQGR
KGEPGEGAYV YRSAFSVGLE TYVTIPNMPI RFTKIFYNQQ NHYDGSTGKF
HCNIPGLYYF AYHITVYMKD VKVSLFKKDK AMLFTYDQYQ ENNVDQASGS
VLLHLEVGDQ VWLQVYGEGE RNGLYADNDN DSTFTGFLLY HDTN
UCSC uc003fra.4; human.;

Human ADIPOQ ELISA Kit

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