Human F11R ELISA Kit

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  • Alternative name

    Human JAM-A ELISA Kit;Human junctional adhesion molecule 1 ELISA Kit;Human JAM-1 ELISA Kit;Human platelet F11 receptor ELISA Kit;Human platelet adhesion molecule 1 ELISA Kit;Human PAM-1 ELISA Kit;Human JAM1 ELISA Kit;Human JCAM ELISA Kit;Human CD321 ELISA Kit;Human JAM ELISA Kit;Human JAMA ELISA Kit;Human KAT ELISA Kit;Human F11 receptor ELISA Kit;Human junctional adhesion molecule A ELISA Kit;

  • Catalog
    E007433
  • species
    Human
  • GeneF11R
  • Other Species Mouse F11r ELISA KitBovine F11R ELISA KitRat F11r ELISA Kit
  • SpecificityThe Human CD321 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human CD321 proteins within the range of 46.9 pg/ml - 3000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity10 pg/ml.
  • Intended UseHuman F11R ELISA Kit allows for the in vitro quantitative determination of F11R , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the Assay||The Human CD321 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human CD321 in Cell Culture Supernatants, Serum. This assay employs an antibody specific for Human CD321 coated on a 96-well plate. Standards and samples are pipetted into the wells and CD321 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human CD321 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of CD321 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: Junctional adhesion molecule A (JAM-A) is a protein that in humans is encoded by the F11R gene. It is mapped to 1q23.3. This gene is an immunoglobulin-like molecule that colocalizes with tight junctions in endothelium and epithelium and is also found on blood leukocytes and platelets. JAM-A plays an important role in the regulation of tight junction assembly in epithelia. In addition, it can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. JAM-A has a nonredundant role in controlling DC motility, trafficking to lymph nodes, and activation of specific immunity.
  • Human Junctional adhesion molecule A Protein information
  • Uniprot ID JAM1_HUMAN
  • Uniprot AC Q9Y624; B7Z941;
  • UniGene Hs.517293;
  • GeneID 50848
  • KEGG hsa:50848;
  • Human Junctional adhesion molecule A Protein SEQUENCE
  • SEQUENCE 299 AA; 32583 MW; D95DE2FEA23D2851 CRC64;

    MGTKAQVERK LLCLFILAIL LCSLALGSVT VHSSEPEVRI PENNPVKLSC

    AYSGFSSPRV EWKFDQGDTT RLVCYNNKIT ASYEDRVTFL PTGITFKSVT

    REDTGTYTCM VSEEGGNSYG EVKVKLIVLV PPSKPTVNIP SSATIGNRAV

    LTCSEQDGSP PSEYTWFKDG IVMPTNPKST RAFSNSSYVL NPTTGELVFD

    PLSASDTGEY SCEARNGYGT PMTSNAVRME AVERNVGVIV AAVLVTLILL

    GILVFGIWFA YSRGHFDRTK KGTSSKKVIY SQPSARSEGE FKQTSSFLV

  • UCSC uc009wtt.4; human. [Q9Y624-1];



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